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  3. Nermin Albalbeisi

  • The Role of PAD2 in Ovarian Cancer

    Ovarian cancer is the fifth most common cause of death among all malignancies in women. Our group has data demonstrating that peptidylarginine deiminase 2 (PAD2) expression in ovarian cancer is associated with patient prognosis and represents an independent prognostic marker. PAD2 mediates citrullination of arginine to citrulline amino acids in proteins. Changes in PAD2 expression/localization within the cell may alter gene expression leading to cancer development. We are also testing the hypothesis that PAD2 expression in ovarian cancer may flag the cancer for destruction by the immune system.


  • Lee Machado

    Professor of Molecular Medicine

  • This research will be completed in collaboration with Northampton General NHS Trust facilities and expertise.

  • After completing an undergraduate degree at University of Jordan and an MSc at Coventry University. Nina is currently a PhD student at The university of Northampton. She started her PhD course in 2015. Her PhD research area is in Cancer biology.