Staff Directory: Dr Stuart Allen
- BSc (Hons) Biology (Portsmouth 1996)
- PhD in Molecular Biology (Warwick 1999)
- Postgraduate Certificate in Academic and Professional Practice (PCAPP) (Warwick 2008)
- Postgraduate Certificate in Research Degree Supervision (Northampton 2010)
The title of the PhD thesis: Isolation and characterisation of a novel histone acetyltransferase complex.
- Molecular Biology
- Genetics and Immunology
- HLS1013 - Health and Disease 1
- HLS3009 - Immunology and Health
- HLS4008/9/10 - Dissertation
- HLS1012 - Intergrated Physiology
- HLS1003 - Molecular Biology of the Cell
- HLS2002 - Biological Basis of Behaviour
- HLS1014 - Research Skills in Biology
- MSc Human Bioscience
- MSc Public Health
Using advanced molecular biology techniques, we hope to isolate candidate genes that are involved in the 'resistance' of antimicrobials. Novel antimicrobials have been developed at the University and are effective against certain bacteria and fungi. Some bacteria and fungi are less well affected by the antimicrobial and this is thought to be due to altered gene regulation. Similarly, affected organisms show a form of resistance over time to the antimicrobial. We hope to isolate genes that have altered transcript levels to determine the mechanisms involved in the 'resistance' phenotype.
The fission yeast Schizosaccharomyces pombe are also used as a model organism. This line of research involves analysis of an interesting phenotype observed in mating experiments. Strains harbouring genetic modification in cell division genes show this altered phenotype. Our research aims to address this by means of rescuing the phenotype using genetic cross to establish genes involved in the regulation of cell division. This research is in collaboration with the University of Warwick.
Publications on NECTAR
- Lama, A., Bates, M. P., Covington, A. D., Allen, S. C. H. and Antunes, A. P. M. (2013) Methods of isolation and identification of pathogenic and potential pathogenic bacteria from skins and tannery effluents. Journal of the American Leather Chemists Association. 108(2), pp. 48-62. 0002-9726.
- Lama, A., Allen, S. C. H., Attenburrow, G. E., Bates, M. P., Covington, A. D. and Antunes, A. P. M. (2012) Survival and growth of Bacillus cereus, Pseudomonas aeruginosa and Staphylococcus aureus in extreme environments present during the early stages of a conventional leather making process. Journal of American Leather Chemists Association. 107(6), pp. 186-195. 0002-9726.
- Adukwu, E., Allen, S. C. H. and Phillips, C. (2012) The anti-biofilm activity of lemongrass (cymbopogon flexussus) and grapefruit (citrus paradisi) essential oils against five strains of staphylococcus aureus. Journal of Applied Microbiology. 113(5), pp. 1217-1227. 1365-2672.
- Phillips, C., Laird, K. and Allen, S. C. H. (2012) The use of Citri-V™® - an antimicrobial citrus essential oil vapour for the control of Penicillium chrysogenum, Aspergillus niger and Alternaria alternata in vitro and on food. Food Research International. 47(2), pp. 310-314. 0963-9969.
- Lama, A., Attenburrow, G. E., Bates, M. P., Covington, A. D., Allen, S. C. H. and Antunes, A. P. M. (2011) Methods of isolation and identification of pathogenic and potential pathogenic bacteria from animal skins and tannery effluents. Paper presented to: XXXI International Union of Leather Technologists and Chemists Societies (IULTCS) Congress, Valencia, Spain, 27-30 September 2011. Also delivered as an Oral presentation at this conference
- Lama, A., Attenburrow, G. E., Bates, M. P., Covington, A. D., Allen, S. C. H. and Antunes, A. P. M. (2011) Microorganisms: growth in the tannery. Leather International. 213(4816), p. 48. 1473-6314.
- Allen, S. C. H., Ollerton, J., Murray, T. and Wayne, S. (2010) A new 3D immersive environment for visualising biological data. Paper presented to: Biological Sciences Research Council/Arts & Humanities Research Council (BBSRC/AHRC) Workshop on The Challenges of Visualising Data, Bristol, England, 16-17 November 2010.
- Li, S., Spooner, R. A., Allen, S. C. H., Guise, C. P., Ladds, G., Schnoder, T., Schmitt, M. J., Lord, J. M. and Roberts, R. M. (2010) Folding-competent and folding-defective forms of Ricin A Chain have different fates after retrotranslocation from the Endoplasmic Reticulum. Molecular Biology of the Cell. 21(15), pp. 2543-2554. 1059-1524.
- Phillips, C., Laird, K. and Allen, S. C. H. (2010) The effect of an essential oil vapour on the growth of Penicillium chrysogenum, Aspergillus niger and Alternaria alternata in vitro and on food. Paper presented to: 15th International Union of Food Science and Technology (IUFoST) Congress, Cape Town, South Africa, 22-26 August 2010.
- Lama, A., Allen, S. C. H., Attenburrow, G. E., Bates, M. P., Covington, A. D. and Antunes, A. P. M. (2009) The impact of beamhouse processes on bacterial growth. Workshop presented to: XXX Congress of the International Union of Leather Technologists and Chemists Societies (IULTCS), Beijing, China, 11-14 October 2009. Beijing, China: China Leather Industry Association.
- Allen, S. C. H., Moore, K. A. H., Marsden, C. J., Fulop, V., Moffat, K. G., Lord, J. M., Ladds, G. and Roberts, L. M. (2007) The isolation and characterisation of temperature dependant ricin A chain mutants in Saccharomyces cerevisiae. FEBS Journal. 274(21), pp. 5586-5599. 1742-464X.
- Li, S., Spooner, R.A., Allen, S.C.H., Guise, C.P., Ladds, G., Schnoder, T., Schmitt, M.J., Lord, J.M. and Roberts, L.M. (2010) Folding-competent and Folding-defective Forms of Ricin A Chain Have Different Fates after Retrotranslocation from the Endoplasmic Reticulum. Mol Biol Cell. 21: 2543-2554
- Allen, S.C.H., Moore, K.A.H., Marsden, C.J., Fulup, V., Lord, J,M., Ladds, G and Roberts, L.M. (2007). The isolation and characterisation of temperature dependant ricin A chain mutants in Saccharomyces cerevisiae. FEBS Journal. 274, 5586-5599
- Allen, S.C.H., Byron, A., Lord, J.M., Davey, J., Roberts, L.M. and Ladds, G. (2005). Utilisation of the budding yeast Saccharomyces cerevisiae for the generation and isolation of non-lethal ricin A chain variants. Yeast. 22, (16): 1287-1297
- Allen, S.C.H. and Hebbes, T.R. (2003). Myb induced myeloid protein 1 (Mim-1) is an acetyltransferase. FEBS Lett. 534, (1-3): 119-124
- Allen, S.C.H., Barrett, C.M., Ray, N. and Robinson, C. (2002). Essential cytoplasmic domains in the Escherichia coli TatC protein. J Biol Chem. 277, (12): 10362-10366
- Hebbes, T.R. and Allen, S.C.H. (2000). Multiple histone acetyltransferases are associated with a chicken erythrocyte chromatin fraction enriched in active genes. J Biol Chem. 275, (40): 31347-31352
- Allen, S.C.H., Ollerton, J., Murray, T. and Wayne. S. (2010) A new 3D immersive environment for visualising biological data. BBSRC, Visualising Biological Data, Bristol
- Allen, S.C.H. and Ekberg, M.E. (2009) Knowledge and understanding of prenatal genetic testing among student midwives. School of Health Learning and Teaching (Unpublished)
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